Cristiano Ronaldo could face his former team Real Madrid in the Champions League quarter-finals as the draw for the rest of the tournament was made on Friday.
Unless Barca's displays for the remainder of the 2019-20 campaign have a significant upswing, it is understood that it is inevitable Setien will leave his post in the summer.
The 24-year-old is due to complete the Bundesliga season in just 11 days time, but his is not willing to return and play in Champions league despite Leipzig reached the quarter-finals for the first time.